Position statement for the management of comorbidities in psoriasis.

Department of Dermatology, Instituto de Investigación Sanitaria Princesa (IIS-IP), Hospital Universitario de la Princesa, Madrid, Spain. Independent Researcher in Health Services Research, Madrid, Spain. Department of Cardiology, Hospital Clínico Universitario de Valencia, Valencia, Spain. Department of Dermatology, Hospital Universitario la Fe, Valencia, Spain. Department of Dermatology, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain. Department of Nephrology, Fundación Jiménez Díaz, Madrid, Spain. Department of Endocrinology & Clinical Nutrition, Hospitales Universitarios Quirón Madrid & Ruber Juan Bravo, Universidad Europea de Madrid, Madrid, Spain. Department of Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain. Department of Gastroenterology and Hepatology, Hospital La Paz, Madrid, Spain. Department of Psychiatry, Hospital Infanta Leonor, Madrid, Spain. Department of Dermatology, Hospital Universitario 12 de Octubre, Madrid, Spain.

Journal of the European Academy of Dermatology and Venereology : JEADV. 2018;(12):2058-2073

Abstract

BACKGROUND The association between psoriasis and some diseases has become relevant in recent years. Providing appropriate management of psoriasis from an early stage requires prompt diagnosis and treatment of concomitant diseases and to prevent any potential comorbidity. This approach should consider the adverse events of the drugs used to treat psoriasis potentially related to the onset of comorbidities. OBJECTIVE To provide the dermatologist with an accurate and friendly tool for systematizing the diagnosis of psoriasis-associated comorbidities, which generally escapes the scope of the dermatology setting, and to facilitate decision-making about the referral and treatment of patients with comorbidities. METHODS These position statement recommendations were developed by a working group composed of ten experts (four dermatologists, one cardiologist, one rheumatologist, one gastroenterologist, one nephrologist, one endocrinologist and one psychiatrist) and two health services researchers. The expert group selected the psoriasis comorbidities considered according to their relevance in the dermatology setting. The recommendations on diagnostic criteria are based on the current clinical practice guidelines for each of the comorbidities. The information regarding the repercussion of psoriasis medical treatments on associated comorbid diseases was obtained from the summary of product characteristics of each drug. RESULTS Recommendations were developed to detect and refer the following psoriasis comorbidities: psoriatic arthritis, cardiovascular risk factors (diabetes, dyslipidaemia, obesity, hypertension and metabolic syndrome), non-alcoholic fatty liver disease, inflammatory bowel disease, kidney disease and psychological disorders (anxiety and depression). In addition, alcohol consumption and tobacco consumption were included. The tables and figures are precise, easy-to-use tools to systematize the diagnosis of comorbidities in patients with psoriasis and facilitate the decision-making process regarding referral and treatment of patients with an associated disease. CONCLUSION The application of these position statement recommendations will facilitate the dermatologist practice, and benefit psoriasis patients' health and quality of life.

Methodological quality

Publication Type : Review

Metadata

MeSH terms : Psoriasis